https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Androgen receptor expression is required to ensure development of adult Leydig cells and to prevent development of steroidogenic cells with adrenal characteristics in the mouse testis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36888 Wed 15 Jul 2020 11:42:42 AEST ]]> Sertoli cell number defines and predicts germ and Leydig cell population sizes in the adult mouse testis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33983 Wed 04 Sep 2019 09:53:56 AEST ]]> The expanded roles of Sertoli cells: lessons from Sertoli cell ablation models https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35519 Tue 23 Jun 2020 15:31:42 AEST ]]> Modelling steroidogenesis: a framework model to support hypothesis generation and testing across endocrine studies https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32813 Mon 23 Sep 2019 12:29:40 AEST ]]> Sperm proteins and cancer-testis antigens are released by the seminiferous tubules in mice and men https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46185 Mon 14 Nov 2022 10:36:46 AEDT ]]> Sertoli cell-enriched proteins in mouse and human testicular interstitial fluid https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52812 in vivo and validated which of these are likely to arise primarily from Sertoli cells based on relevant mouse testis RNASeq datasets. We used a different, but complementary, approach to identify Sertoli cell-enriched proteins in human TIF, taking advantage of high-quality human testis genomic, proteomic and immunohistochemical datasets. We identified a total of 47 and 40 Sertoli cell-enriched proteins in mouse and human TIF, respectively, including 15 proteins that are conserved in both species. Proteins with potential roles in angiogenesis, the regulation of Leydig cells or steroidogenesis, and immune cell regulation were identified. The data suggests that some of these proteins are secreted, but that Sertoli cells also deposit specific proteins into TIF via the release of extracellular vesicles. In conclusion, we have identified novel Sertoli cell-enriched proteins in TIF that are candidates for regulating somatic cell-cell communication and testis function.]]> Fri 27 Oct 2023 15:56:20 AEDT ]]> Relationship of transcriptional markers to Leydig cell number in the mouse testis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42192 Fri 19 Aug 2022 10:18:17 AEST ]]> Ablation of the canonical testosterone production pathway via knockout of the steroidogenic enzyme HSD17B3, reveals a novel mechanism of testicular testosterone production https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44473 Fri 14 Oct 2022 08:50:28 AEDT ]]>